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将一种微生物定性为益生菌的条件之一是其绝对安全,而证据显示,绝大多数被定性为益生菌的菌株对人类无害。只有在有特殊健康状况的免疫力低下人群中,才应特别小心,并强烈建议听取专业意见。在健康人群的情况下,益生菌作为活的微生物,当施以足够的量时,会给宿主带来健康益处。
今天,像活文化这样的创新应用正在被研究,并在食品和医药等不同领域引起了特别的兴趣。在未来,由于对益生菌菌株进行基因改造的研究和进展,以获得能够在患者肠道内产生活性成分和特定营养物质的重组物种,从而成为活的生物治疗剂,这种分化将被减少。
近年来,在对健康生活的渴望和功能食品概念的刺激下,普通消费者对益生菌的兴趣大大增加。这使人们对富含益生菌的食品产生了强烈的商业兴趣,这些食品构成了功能食品的很大一部分,这个市场继续以指数速度增长,由于近年来进行的大量研究,导致了多种可被称为益生菌的产品的开发。
关于食品和食品补充剂中存在的益生菌菌株的标签,以及潜在的健康益处,有必要考虑到每个国家的立法。目前,西班牙的AESAN已经允许在本国生产的食品和食品补充剂的标签上使用 "益生菌 "一词,只要它们符合第178/2002号法规规定的要求。至于健康声明,只有当特定菌株被EFSA列入名单时才被允许,目前没有任何与食用EFSA批准的益生菌生物体有关的健康益处可供标示,只有酸奶中的微生物被允许。